Williams Hematology

McGraw-Hill

2021

XXIII, 2664 p.

9781260464122

Part I: Clinical Evaluation of the Patient -- Chapter 1: Initial Approach to the Patient: History and Physical Examination -- Chapter 2: Examination of Blood and Marrow Cells -- Chapter 3: Consultative Hematology Part II: The Organization of the Lymphohematopoietic Tissues -- Chapter 4: Structure of the Marrow and the Hematopoietic Microenvironment -- Chapter 5: The Organization and Structure of Lymphoid Tissues Part III: Epochal Hematology -- Chapter 6: Hematology of the Fetus and Newborn -- Chapter 7: Hematology During Pregnancy -- Chapter 8: Hematology in Older Persons Part IV: Molecular and Cellular Hematology -- Chapter 9: Genetic Principles and Molecular Biology -- Chapter 10: Genomics and Epigenomics Chapter 11: Cytogenetic and Genetic Abnormalities -- Chapter 12: Application of Big Data and Deep Learning in Hematology -- Chapter 13: Metabolism of Hematologic Neoplastic Cells -- Chapter 14: Cell Death -- Chapter 15: Cell-Cycle Regulation and Hematologic Disorders -- Chapter 16: Signal Transduction Pathways -- Chapter 17: Hematopoietic Stem Cells, Progenitors, and Cytokines -- Chapter 18: The Inflammatory Response -- Chapter 19: Innate Immunity -- Chapter 20: The Biology of Innate Lymphoid Cells and Natural Killer Cells -- Chapter 21: Dendritic Cells and Adaptive Immunity Part V: Therapeutic Principles -- Chapter 22: Immune Checkpoint Inhibitors -- Chapter 23: Immune Cell Therapy: Chimeric Antigen Receptor T-Cell Therapy -- Chapter 24: Immune Cell Therapy: Dendritic Cell and Natural Killer Cell Therapy -- Chapter 25: Vaccine Therapy -- Chapter 26: Gene Therapy for Hematologic Diseases -- Chapter 27: Regenerative Medicine: Induced Pluripotent Stem Cells And Blood Cell Engineering -- Chapter 28: Pharmacology and Toxicity of Antineoplastic Drugs -- Chapter 29: Hematopoietic Stem Cell Transplantation -- Chapter 30: Therapeutic Apheresis: Indications, Efficacy, and Complications -- Chapter 31: Treatment of Infections in the Immunocompromised Host -- Chapter 32: Antithrombotic Therapy Part VI: The Erythrocyte -- Chapter 33: Structure and Composition of the Erythrocyte -- Chapter 34: Erythropoiesis and Red Cell Turnover -- Chapter 35: Clinical Manifestations and Classification of Erythrocyte Disorders -- Chapter 36: Aplastic Anemia: Acquired and Inherited -- Chapter 37: Pure Red Cell Aplasia -- Chapter 38: Anemia of Chronic Disease -- Chapter 39: Erythropoietic Effects of Endocrine Disorders -- Chapter 40: The Hereditary Dyserythropoietic Anemias -- Chapter 41: Paroxysmal Nocturnal Hemoglobinuria -- Chapter 42: Folate, Cobalamin, and Megaloblastic Anemias -- Chapter 43: Iron Metabolism -- Chapter 44: Iron Deficiency and Overload -- Chapter 45: Anemia Resulting from Other Nutritional Deficiencies -- Chapter 46: Anemia Associated with Marrow Infiltration -- Chapter 47: Erythrocyte Membrane Disorders -- Chapter 48: Erythrocyte Enzyme Disorders -- Chapter 49: Thalassemia: A Disorder of Globin Synthesis -- Chapter 50: Disorders of Hemoglobin Structure: Sickle Cell Anemia and Related Abnormalities -- Chapter 51: Methemoglobinemia and Other Dyshemoglobinemias -- Chapter 52: Fragmentation Hemolytic Anemia -- Chapter 53: Erythrocyte Disorders as a Result of Toxic Agents -- Chapter 54: Hemolytic Anemia Resulting from Infections with Microorganisms -- Chapter 55: Hemolytic Anemia Resulting from Immune Injury -- Chapter 56: Alloimmune Hemolytic Disease of the Fetus and Newborn -- Chapter 57: Hypersplenism and Hyposplenism -- Chapter 58: Primary and Secondary Erythrocytoses/Polycythemias -- Chapter 59: The Porphyrias -- Chapter 60: Polyclonal and Hereditary Sideroblastic Anemias Part VII: Neutrophils, Eosinophils, Basophils, and Mast Cells -- Chapter 61: Structure and Composition of Neutrophils, Eosinophils, and Basophils -- Chapter 62: Classification and Clinical Manifestations of Neutrophil Disorders -- Chapter 63: Neutropenia and Neutrophilia -- Chapter 64: Disorders of Neutrophil Function -- Chapter 65: Eosinophils and Their Disorders -- Chapter 66: Basophils and Mast Cells and Their Disorders Part VIII: Monocytes and Macrophages -- Chapter 67: Structure, Receptors, and Functions of Monocytes and Macrophages -- Chapter 68: Production, Distribution, and Activation of Monocytes and Macrophages -- Chapter 69: Classification and Clinical Manifestations of Disorders of Monocytes and Macrophages -- Chapter 70: Monocytosis and Monocytopenia -- Chapter 71: Inflammatory and Malignant Histiocytosis -- Chapter 72: Gaucher Disease and Related Lysosomal Storage Diseases Part IX: Lymphocytes and Plasma Cells -- Chapter 73: The Structure of Lymphocytes and Plasma Cells -- Chapter 74: Lymphopoiesis -- Chapter 75: Functions of B Lymphocytes and Plasma Cells in Immunoglobulin Production -- Chapter 76: Functions of T Lymphocytes: T-Cell Receptors for Antigen -- Chapter 77: Classification and Clinical Manifestations of Lymphocyte and Plasma Cell Disorders -- Chapter 78: Lymphocytosis and Lymphocytopenia -- Chapter 79: Immunodeficiency Diseases -- Chapter 80: Hematologic Manifestations of Human Immunodeficiency Virus and the Acquired Immunodeficiency Syndrome -- Chapter 81: Mononucleosis Syndromes Part X: Malignant Myeloid Diseases -- Chapter 82: Classification and Clinical Manifestations of the Clonal Myeloid Disorders -- Chapter 83: Polycythemia Vera -- Chapter 84: Essential Thrombocythemia -- Chapter 85: Primary Myelofibrosis -- Chapter 86: Myelodysplastic Syndromes -- Chapter 87: Acute Myelogenous Leukemia -- Chapter 88: Chronic Myelogenous Leukemia and Related Disorders Part XI: Malignant Lymphoid Diseases -- Chapter 89: Classification of Malignant Lymphoid Disorders -- Chapter 90: Acute Lymphoblastic Leukemia -- Chapter 91: Chronic Lymphocytic Leukemia -- Chapter 92: Hairy Cell Leukemia -- Chapter 93: Large Granular Lymphocytic Leukemia -- Chapter 94: General Considerations of Lymphomas: Incidence Rates, Etiology, Diagnosis, Staging, and Primary Extranodal Disease -- Chapter 95: Pathology of Lymphomas -- Chapter 96: Hodgkin Lymphoma -- Chapter 97: Diffuse Large B-Cell Lymphoma and Related Diseases -- Chapter 98: Follicular Lymphoma -- Chapter 99: Mantle Cell Lymphoma -- Chapter 100: Marginal Zone B-Cell Lymphomas -- Chapter 101: Burkitt Lymphoma -- Chapter 102: Cutaneous T-Cell Lymphoma (Mycosis Fungoides and Sézary Syndrome) -- Chapter 103: Mature T-Cell and Natural Killer Cell Lymphomas -- Chapter 104: Plasma Cell Neoplasms: General Considerations -- Chapter 105: Essential Monoclonal Gammopathy -- Chapter 106: Myeloma -- Chapter 107: Immunoglobulin Light Chain Amyloidosis -- Chapter 108: Macroglobulinemia -- Chapter 109: Heavy-Chain Disease Part XII: Hemostasis and Thrombosis -- Chapter 110: Megakaryopoiesis and Thrombopoiesis -- Chapter 111: Platelet Morphology, Biochemistry, and Function -- Chapter 112: Molecular Biology and Biochemistry of the Coagulation Factors and Pathways of Hemostasis -- Chapter 113: Control of Coagulation Reactions -- Chapter 114: Vascular Function in Hemostasis -- Chapter 115: Classification, Clinical Manifestations, and Evaluation of Disorders of Hemostasis -- Chapter 116: Thrombocytopenia -- Chapter 117: Heparin-Induced Thrombocytopenia -- Chapter 118: Hereditary and Reactive Thrombocytosis -- Chapter 119: Inherited Platelet Disorders -- Chapter 120: Acquired Qualitative Platelet Disorders -- Chapter 121: The Vascular Purpuras -- Chapter 122: Hemophilia A and Hemophilia B -- Chapter 123: Inherited Deficiencies of Coagulation Factors II, V, V+VIII, VII, X, XI, and XIII -- Chapter 124: Hereditary Fibrinogen Abnormalities -- Chapter 125: VON Willebrand Disease -- Chapter 126: Antibody-Mediated Coagulation Factor Deficiencies -- Chapter 127: Disseminated Intravascular Coagulation -- Chapter 128: Thrombotic Microangiopathies -- Chapter 129: Hemolytic Uremic Syndrome -- Chapter 130: Hemostatic Alterations In Liver Diseases and Liver Transplantation -- Chapter 131: Hereditary Thrombophilia -- Chapter 132: The Antiphospholipid Syndrome --Chapter 133: Venous Thrombosis -- Chapter 134: Atherothrombosis: Disease Initiation, Progression, and Treatment -- Chapter 135: Fibrinolysis and Thrombolysis Part XIII: Transfusion Medicine -- Chapter 136: Erythrocyte Antigens and Antibodies -- Chapter 137: Human Leukocyte and Platelet Antigens -- Chapter 138: Blood Procurement and Red Cell Transfusion Chapter 139: Preservation and Clinical use of Platelets -- Chapter 140: Using Plasma and Plasma Component Therapy.

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